Ideal for Drugs with a Narrow Absorption Window
The Accordion Pill platform technology is designed to increase the time that drugs are retained in the stomach as compared to other oral dosage forms, such as tablets and capsules. This capability is particularly important to drugs with a narrow absorption window (“NAW”), which are absorbed mainly in the upper part of the gastrointestinal, or GI, tract.
Regular controlled-release formulations of such drugs currently on the market sometimes fail to provide an efficient solution, as once the regular dosage form has passed the drug’s NAW in the upper GI tract, the drug is not, or is very poorly, absorbed in the distal parts of the GI tract.
The Accordion Pill’s efficient gastric retention and specific release mechanism prolongs the absorption phase of drugs with an NAW, which can result in significantly more stable plasma levels.